Reactome | D'Eustachio, Peter, 2025-01-30

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D'Eustachio, Peter, 2025-01-30 Show undefined attributes

author	[Person:140934] D'Eustachio, P
dateTime	2025-01-30 13:42:16
dbId	9937296
displayName	D'Eustachio, Peter, 2025-01-30
schemaClass	InstanceEdit

Referrals

(author)	[Person:140934] D'Eustachio, P
(internalReviewed)	[Pathway:R-HSA-9769726] Defects of Coagulation cascade [Pathway:R-HSA-9936686] Aggregated ?-amyloid interacts with fibrinogen [Reaction:R-HSA-9936699] fibrinogen + ?-amyloid fibril:Zn2+ -> fibrinogen:?-amyloid fibril:Zn2+ [Reaction:R-HSA-9939011] Lecanemab binds amyloid ? protein (APP) protofibrils [Pathway:R-HSA-9930483] Defective FV causes thrombophilia [Pathway:R-HSA-9930479] Defective cleavage of FV variant at R334 [FailedReaction:R-HSA-9930440] F5 R334T, I387T is not cleaved by activated protein C [Pathway:R-HSA-9930449] Defective cleavage of FV variant at a.a.534 [FailedReaction:R-HSA-9930452] F5 R534Q, A540V is not cleaved by activated protein C [Pathway:R-HSA-9853846] Defective ANO6 does not expose PS, PE on the platelet membrane [Pathway:R-HSA-9769740] Coagulation pathway [Reaction:R-HSA-140791] activated thrombin (factor IIa) + antithrombin III:heparan sulfate -> thrombin:antithrombin III:heparan sulfate [Pathway:R-HSA-9769735] Initiation of coagulation cascade [Reaction:R-HSA-9822522] factor VIII -> factor VIIIa + factor VIII B chain+ factor VIII A3 acidic polypeptide +VWF multimer (TF:FVIIa:FXa catalyst) [FailedReaction:R-HSA-9853849] Defective ANO6 does not expose PS, PE on the platelet membrane [Reaction:R-HSA-9929054] TF:FVIIa:FIXa ->TF:FVIIa + FIXa
(structureModified)	[Pathway:R-HSA-446199] Synthesis of dolichyl-phosphate [Reaction:R-HSA-4419978] DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP

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