Reactome | 'canonical' WNT target genes [nucleoplasm]

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'canonical' WNT target genes [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8944354] 'canonical' WNT target genes:TCF/LEF [nucleoplasm] - Homo sapiens [Complex:R-HSA-8944361] 'canonical' WNT target genes:TCF/LEF:CTNNB1 [nucleoplasm] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-5229348] Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes - Homo sapiens [Reaction:R-HSA-8944352] TCF/LEF binds WNT promoters - Homo sapiens [BlackBoxEvent:R-HSA-4411365] Transcription of canonical WNT targets is negatively regulated by NLK-dependent phosphorylation of TCF/LEF - Homo sapiens [Reaction:R-HSA-8944362] TCF/LEF:CTNNB1 bind canonical WNT target promoters - Homo sapiens
created	[InstanceEdit:4411356] Rothfels, K, 2013-08-23
dbId	4411390
displayName	'canonical' WNT target genes [nucleoplasm]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-4411327] AXIN2 gene [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2127254] MYC gene [nucleoplasm] - Homo sapiens
inDisease	false
inferredTo	[GenomeEncodedEntity:R-MMU-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Mus musculus [GenomeEncodedEntity:R-RNO-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Rattus norvegicus [GenomeEncodedEntity:R-CFA-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Canis familiaris [GenomeEncodedEntity:R-BTA-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Bos taurus [GenomeEncodedEntity:R-SSC-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Sus scrofa [GenomeEncodedEntity:R-DRE-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Danio rerio [GenomeEncodedEntity:R-XTR-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Xenopus tropicalis [GenomeEncodedEntity:R-GGA-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Gallus gallus [GenomeEncodedEntity:R-DME-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Drosophila melanogaster [GenomeEncodedEntity:R-CEL-4411390] Ghost homologue of 'canonical' WNT target genes [nucleoplasm] - Caenorhabditis elegans
maxDepth	2
modified	[InstanceEdit:8944381] Rothfels, Karen, 2016-11-03
name	'canonical' WNT target genes
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-4411390
updateTrackers	[UpdateTracker:9889370] Update Tracker - [CandidateSet:4411390] 'canonical' WNT target genes [nucleoplasm] - v48:[modifyName, updateContainedMemberOrCandidate] [UpdateTracker:9895443] Update Tracker - [CandidateSet:4411390] 'canonical' WNT target genes [nucleoplasm] - v59:[add_removeHasCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9889370] Update Tracker - [CandidateSet:4411390] 'canonical' WNT target genes [nucleoplasm] - v48:[modifyName, updateContainedMemberOrCandidate] [UpdateTracker:9895443] Update Tracker - [CandidateSet:4411390] 'canonical' WNT target genes [nucleoplasm] - v59:[add_removeHasCandidate]
(input)	[BlackBoxEvent:R-HSA-5229348] Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes [Reaction:R-HSA-8944352] TCF/LEF binds WNT promoters [BlackBoxEvent:R-HSA-4411365] Transcription of canonical WNT targets is negatively regulated by NLK-dependent phosphorylation of TCF/LEF [Reaction:R-HSA-8944362] TCF/LEF:CTNNB1 bind canonical WNT target promoters
(hasComponent)	[Complex:R-HSA-8944354] 'canonical' WNT target genes:TCF/LEF [nucleoplasm] [Complex:R-HSA-8944361] 'canonical' WNT target genes:TCF/LEF:CTNNB1 [nucleoplasm]

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