Reactome | Activation of MAP3K7 in response to WNT

Schema > BlackBoxEvent > Entries

Activation of MAP3K7 in response to WNT Show undefined attributes

authored	[InstanceEdit:4086406] Rothfels, K, 2013-08-07
catalystActivity	[CatalystActivity:5250906] protein serine/threonine kinase activity of unknown kinase [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4332389] Rothfels, K, 2013-08-16
dbId	4332388
displayName	Activation of MAP3K7 in response to WNT
edited	[InstanceEdit:4663813] Matthews, L, 2013-10-07
eventOf	[Pathway:R-HSA-4086398] Ca2+ pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-4411402] Activation of NLK - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-4332361] p-T286,305,306-CAMK2:MAP3K7 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4332244] The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling [LiteratureReference:4332321] TAK1, more than just innate immunity
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation of MAP3K7 in response to WNT
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-HSA-206014] p-T187-MAP3K7 [cytosol] [Complex:R-HSA-4332355] p-T286,T305,T306-CAMK2A [cytosol]
precedingEvent	[Reaction:R-HSA-4332356] CAMK2 binds MAP3K7 - Homo sapiens
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-4332388
summation	[Summation:4332364] Endogenous MAP3K7 is phosphorylated in a CAMK2-dependent fas...
updateTrackers	[UpdateTracker:9786701] Update Tracker - [BlackBoxEvent:4332388] Activation of MAP3K7 in response to WNT - v48:[add_removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9786701] Update Tracker - [BlackBoxEvent:4332388] Activation of MAP3K7 in response to WNT - v48:[add_removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-4086398] Ca2+ pathway
(precedingEvent)	[Reaction:R-HSA-4411402] Activation of NLK [NegativePrecedingEvent:9864368] Futile Cycle: Activation of MAP3K7 in response to WNT

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