Reactome | p-T497,T638,S657-PRKCA [cytosol]

Schema > EntityWithAccessionedSequence > Entries

p-T497,T638,S657-PRKCA [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9010778] p-S1330-ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] - Homo sapiens [Complex:R-HSA-9010732] ROBO2:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9010643] AKAP5 recruits PKC to ROBO2 - Homo sapiens [Reaction:R-HSA-9010646] AKAP5 recruits PKC to ROBO3.1 - Homo sapiens [Reaction:R-HSA-4332390] Translocation and activation of PKC alpha in response to WNT signaling - Homo sapiens
created	[InstanceEdit:4332336] Rothfels, K, 2013-08-16
dbId	4332337
displayName	p-T497,T638,S657-PRKCA [cytosol]
endCoordinate	672
hasModifiedResidue	[ModifiedResidue:4332335] O-phospho-L-threonine at 497 [ModifiedResidue:4332338] O-phospho-L-threonine at 638 [ModifiedResidue:4332339] O-phospho-L-serine at 657
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9010746] p-T497,T638,S657-Prkca [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-SSC-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DME-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-4332337-2] phospho-p-T497,T638,S657-PRKCA [cytosol] - Drosophila melanogaster [DefinedSet:R-DME-4332337-3] Homologues of p-T497,T638,S657-PRKCA [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-4332337-2] phospho-p-T497,T638,S657-PRKCA [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-4332337-3] Homologues of p-T497,T638,S657-PRKCA [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-4332337-2] phospho-p-T497,T638,S657-PRKCA [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SPO-4332337-3] Homologues of p-T497,T638,S657-PRKCA [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Saccharomyces cerevisiae
literatureReference	[LiteratureReference:4332315] Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1) [LiteratureReference:4332313] Protein kinase C is regulated in vivo by three functionally distinct phosphorylations
maxDepth	1
memberOf	[DefinedSet:R-HSA-5218758] p-PKC [cytosol] - Homo sapiens
modified	[InstanceEdit:9010735] Orlic-Milacic, Marija, 2017-06-28
name	p-T497,T638,S657-PRKCA Protein kinase C, alpha type PKC-alpha PKC-A
referenceEntity	[ReferenceGeneProduct:uniprot:P17252] UniProt:P17252 PRKCA
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-4332337
startCoordinate	2
updateTrackers	[UpdateTracker:9897649] Update Tracker - [EntityWithAccessionedSequence:4332337] p-T497,T638,S657-PRKCA [cytosol] - v62:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9897649] Update Tracker - [EntityWithAccessionedSequence:4332337] p-T497,T638,S657-PRKCA [cytosol] - v62:[modifyName]
(hasComponent)	[Complex:R-HSA-9010732] ROBO2:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] [Complex:R-HSA-9010778] p-S1330-ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] [Complex:R-HSA-9010754] ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane]
(input)	[Reaction:R-HSA-9010643] AKAP5 recruits PKC to ROBO2 [Reaction:R-HSA-9010646] AKAP5 recruits PKC to ROBO3.1 [Reaction:R-HSA-4332390] Translocation and activation of PKC alpha in response to WNT signaling
(activeUnit)	[CatalystActivity:9010774] calcium,diacylglycerol-dependent serine/threonine kinase activity of ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-5218758] p-PKC [cytosol]

Cite Us!