Reactome | Recruitment of ERCC6 (CSB), EHMT2 (G9a), and NuRD to the promoter of rRNA gene

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Recruitment of ERCC6 (CSB), EHMT2 (G9a), and NuRD to the promoter of rRNA gene Show undefined attributes

authored	[InstanceEdit:427423] May, B, 2009-06-21
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:427372] May, B, 2009-06-19
dbId	427404
displayName	Recruitment of ERCC6 (CSB), EHMT2 (G9a), and NuRD to the promoter of rRNA gene
edited	[InstanceEdit:427381] May, B, 2009-06-19
eventOf	[Pathway:R-HSA-427389] ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression - Homo sapiens
followingEvent	[Reaction:R-HSA-427336] TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9 - Homo sapiens
inferredFrom	[Reaction:R-NUL-573385] Recruitment of CSB, G9a, and NuRD to the rRNA promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-212151] EHMT2 [nucleoplasm] [Complex:R-HSA-5365864] ERCC6 dimer [nucleoplasm] [Complex:R-HSA-4657018] NuRD complex [nucleoplasm] [Complex:R-HSA-74977] TTF-I:Sal Box [nucleoplasm]
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:565761] Truncated Cockayne syndrome B protein represses elongation by RNA polymerase I [LiteratureReference:5096447] Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription [LiteratureReference:5365873] CSB is a component of RNA pol I transcription
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Recruitment of ERCC6 (CSB), EHMT2 (G9a), and NuRD to the promoter of rRNA gene
output	[Complex:R-HSA-427352] TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm]
precedingEvent	[Reaction:R-HSA-74987] TTF-I binds to the Sal Box - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8856904] Iben, Sebastian, 2016-02-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-427404
summation	[Summation:427431] Transcription Termination Factor-I (TTF-I) is a sequence-spe...

Referrals

(hasEvent)	[Pathway:R-HSA-427389] ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
(precedingEvent)	[Reaction:R-HSA-427336] TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9
(inferredTo)	[Reaction:R-NUL-573385] Recruitment of CSB, G9a, and NuRD to the rRNA promoter

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