Reactome | CBX3 [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-427344] Chromatin (H3K9me2):CBX3 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9007446] PRC1L4 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-427383] CBX3 (HP1gamma) binds histone H3 dimethylated at lysine-9 - Homo sapiens [Reaction:R-HSA-9007283] CBX3 and PRC1.6 associate with E2F6.com-1 - Homo sapiens [Reaction:R-HSA-9007447] E2F6 forms the PRC1L4 complex - Homo sapiens
created	[InstanceEdit:427372] May, B, 2009-06-19
dbId	427386
displayName	CBX3 [nucleoplasm]
endCoordinate	183
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-573362] Cbx3 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-427386] Cbx3 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-427386] CBX3 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-427386] CBX3 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-427386] CBX3 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-GGA-427386] CBX3 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-427386] HP1b [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-427386] hpl-1 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-427386] hcpC [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-427386] swi6 [nucleoplasm] - Schizosaccharomyces pombe [GenomeEncodedEntity:R-SCE-427386] Ghost homologue of CBX3 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-427386] CBX3 [nucleoplasm] - Plasmodium falciparum
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	CBX3 HP1gamma Chromobox protein homolog 3 CBX3_HUMAN
referenceEntity	[ReferenceGeneProduct:51520] UniProt:Q13185 CBX3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-427386
startCoordinate	1

(hasComponent)	[Complex:R-HSA-427344] Chromatin (H3K9me2):CBX3 [nucleoplasm] [Complex:R-HSA-9007446] PRC1L4 [nucleoplasm] [Complex:R-HSA-8953987] E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6 [nucleoplasm]
(input)	[Reaction:R-HSA-427383] CBX3 (HP1gamma) binds histone H3 dimethylated at lysine-9 [Reaction:R-HSA-9007447] E2F6 forms the PRC1L4 complex [Reaction:R-HSA-9007283] CBX3 and PRC1.6 associate with E2F6.com-1
(activeUnit)	[NegativeGeneExpressionRegulation:R-HSA-8953585] Negative gene expression regulation by 'E2F6:TFDP1/2,(E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6) [nucleoplasm]'

CBX3 [nucleoplasm] Show undefined attributes

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