Reactome | Cation influx mediated by TRPC3/6/7

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Cation influx mediated by TRPC3/6/7 Show undefined attributes

authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:426224] monoatomic cation channel activity of DAG-activated TRPC3/6/7 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:426227] Jupe, S, 2009-06-12
crossReference	[DatabaseIdentifier:12667893] RHEA:34963 [DatabaseIdentifier:12667421] RHEA:29671 [DatabaseIdentifier:12668187] RHEA:29827
dbId	426223
displayName	Cation influx mediated by TRPC3/6/7
edited	[InstanceEdit:870305] Jupe, S, 2010-06-07
eventOf	[Pathway:R-HSA-139853] Elevation of cytosolic Ca2+ levels - Homo sapiens
followingEvent	[Reaction:R-HSA-114553] Activation of conventional Protein Kinase C - Homo sapiens
input	[DefinedSet:R-ALL-426219] Cations [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:426225] trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry [LiteratureReference:426211] Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol [LiteratureReference:426195] Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Cation influx mediated by TRPC3/6/7
orthologousEvent	[Reaction:R-CEL-426223] Cation influx mediated by TRPC3/6/7 - Caenorhabditis elegans [Reaction:R-GGA-426223] Cation influx mediated by TRPC3/6/7 - Gallus gallus [Reaction:R-XTR-426223] Cation influx mediated by TRPC3/6/7 - Xenopus tropicalis [Reaction:R-DRE-426223] Cation influx mediated by TRPC3/6/7 - Danio rerio [Reaction:R-SSC-426223] Cation influx mediated by TRPC3/6/7 - Sus scrofa [Reaction:R-BTA-426223] Cation influx mediated by TRPC3/6/7 - Bos taurus [Reaction:R-CFA-426223] Cation influx mediated by TRPC3/6/7 - Canis familiaris [Reaction:R-RNO-426223] Cation influx mediated by TRPC3/6/7 - Rattus norvegicus [Reaction:R-MMU-426223] Cation influx mediated by TRPC3/6/7 - Mus musculus
output	[DefinedSet:R-ALL-426221] Cations [cytosol]
precedingEvent	[Reaction:R-HSA-426209] DAG activation of TRPC channels - Homo sapiens
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-426223
summation	[Summation:426226] TRP channels are non-selectively permeable to cations, allow...

Referrals

(hasEvent)	[Pathway:R-HSA-139853] Elevation of cytosolic Ca2+ levels
(precedingEvent)	[Reaction:R-HSA-114553] Activation of conventional Protein Kinase C