Reactome | Cation influx mediated by TRPC3/6/7

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Cation influx mediated by TRPC3/6/7 Show undefined attributes

catalystActivity	[CatalystActivity:10936586] monoatomic cation channel activity of DAG-activated TRPC3/6/7 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10936588
displayName	Cation influx mediated by TRPC3/6/7
eventOf	[Pathway:R-CEL-139853] Elevation of cytosolic Ca2+ levels - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-114553] Activation of conventional Protein Kinase C - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-426223] Cation influx mediated by TRPC3/6/7 - Homo sapiens
input	[DefinedSet:R-ALL-426219] Cations [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Cation influx mediated by TRPC3/6/7
output	[DefinedSet:R-ALL-426221] Cations [cytosol]
precedingEvent	[Reaction:R-CEL-426209] DAG activation of TRPC channels - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-426223
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-139853] Elevation of cytosolic Ca2+ levels
(precedingEvent)	[Reaction:R-CEL-114553] Activation of conventional Protein Kinase C
(inferredTo)	[Reaction:R-HSA-426223] Cation influx mediated by TRPC3/6/7

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