Reactome | trans-Golgi Network Derived Vesicle Uncoating

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trans-Golgi Network Derived Vesicle Uncoating Show undefined attributes

authored	[InstanceEdit:434217] Gillespie, ME, 2009-08-27
category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:421834] Gillespie, ME, 2009-05-21 20:11:24
dbId	421836
displayName	trans-Golgi Network Derived Vesicle Uncoating
edited	[InstanceEdit:351199] Gillespie, ME, 2008-05-21 20:31:41
eventOf	[Pathway:R-HSA-432722] Golgi Associated Vesicle Biogenesis - Homo sapiens
followingEvent	[Reaction:R-HSA-376364] Vamp8 associated secretory vesicle to plasma membrane transport - Homo sapiens [Reaction:R-HSA-376369] Vamp2 associated secretory vesicle to plasma membrane transport - Homo sapiens [Reaction:R-HSA-434362] Recruitment Of Cytoplasmic Proteins To Vesicles - Homo sapiens [Reaction:R-HSA-429815] Formation Of Bloc-1 Complex - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-351198] Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] [Complex:R-HSA-351175] HSC70:Auxillin Complex [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:351764] Role of auxilin in uncoating clathrin-coated vesicles [LiteratureReference:351730] Alteration of clathrin light chain expression by transfection and gene disruption [LiteratureReference:351763] Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors [LiteratureReference:70143] Regulated transport of the glucose transporter GLUT4 [LiteratureReference:434354] Comparative proteomics of clathrin-coated vesicles
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	trans-Golgi Network Derived Vesicle Uncoating
orthologousEvent	[Reaction:R-GGA-421836] trans-Golgi Network Derived Vesicle Uncoating - Gallus gallus [Reaction:R-CFA-421836] trans-Golgi Network Derived Vesicle Uncoating - Canis familiaris [Reaction:R-RNO-421836] trans-Golgi Network Derived Vesicle Uncoating - Rattus norvegicus [Reaction:R-MMU-421836] trans-Golgi Network Derived Vesicle Uncoating - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] 52 × [Complex:R-HSA-167717] AP-1 Complex [cytosol] 52 × [EntityWithAccessionedSequence:R-HSA-264470] ARRB1 [cytosol] 48 × [Complex:R-HSA-350827] Clathrin Triskelion [cytosol] 52 × [CandidateSet:R-HSA-435029] Golgi-associated Vesicle Cargo [cytoplasmic vesicle lumen] 52 × [CandidateSet:R-HSA-432672] Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] [Complex:R-HSA-351175] HSC70:Auxillin Complex [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] 52 × [CandidateSet:R-HSA-432673] Vamp [cytoplasmic vesicle membrane]
precedingEvent	[Reaction:R-HSA-421835] trans-Golgi Network Vesicle Scission - Homo sapiens
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:434284] Simpson, Jeremy C, 2009-08-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-421836
summation	[Summation:421832] The heat shock protein Hsc70 and auxilin, a J-domain contain...

Referrals

(precedingEvent)	[Reaction:R-HSA-376364] Vamp8 associated secretory vesicle to plasma membrane transport [Reaction:R-HSA-376369] Vamp2 associated secretory vesicle to plasma membrane transport [Reaction:R-HSA-434362] Recruitment Of Cytoplasmic Proteins To Vesicles [Reaction:R-HSA-429815] Formation Of Bloc-1 Complex
(hasEvent)	[Pathway:R-HSA-432722] Golgi Associated Vesicle Biogenesis

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