Reactome | Negative gene expression regulation by 'NR1D1:heme:Corepressors:ARNTL gene [nucleoplasm]'

Schema > NegativeGeneExpressionRegulation > Entries

created	[InstanceEdit:421345] May, B, 2009-05-17 21:29:40
dbId	421342
displayName	Negative gene expression regulation by 'NR1D1:heme:Corepressors:ARNTL gene [nucleoplasm]'
modified	[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
regulatedEntity	[BlackBoxEvent:R-HSA-9911580] RORA,B,C positively regulates expression and NR1D1 (REV-ERBA) negatively regulates expression of BMAL1 (ARNTL) - Homo sapiens [BlackBoxEvent:R-HSA-400342] Expression of BMAL1 (ARNTL) - Homo sapiens
regulator	[Complex:R-HSA-5663269] NR1D1:heme:Corepressors:ARNTL gene [nucleoplasm]
schemaClass	NegativeGeneExpressionRegulation
stId	R-HSA-421342

(regulation)	[RegulationReference:9643028] Negative gene expression regulation by 'NR1D1:heme:Corepressors:ARNTL gene [nucleoplasm]' Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta
(regulatedBy)	[BlackBoxEvent:R-HSA-400342] Expression of BMAL1 (ARNTL) [BlackBoxEvent:R-HSA-9911580] RORA,B,C positively regulates expression and NR1D1 (REV-ERBA) negatively regulates expression of BMAL1 (ARNTL)

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