Reactome | A1 and A3 receptors bind adenosine

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A1 and A3 receptors bind adenosine Show undefined attributes

authored	[InstanceEdit:418916] Jassal, Bijay, 2009-04-27
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:418916] Jassal, Bijay, 2009-04-27
dbId	418904
displayName	A1 and A3 receptors bind adenosine
edited	[InstanceEdit:418916] Jassal, Bijay, 2009-04-27
eventOf	[Pathway:R-HSA-417973] Adenosine P1 receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[SimpleEntity:R-ALL-83908] Ade-Rib [extracellular region] [DefinedSet:R-HSA-418922] ADORA1,3 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:418899] Cloning and functional characterization of a human A1 adenosine receptor [LiteratureReference:418903] Molecular cloning and characterization of the human A3 adenosine receptor [LiteratureReference:418938] Comparative analysis of the efficacy of A1 adenosine receptor activation of Gi/o alpha G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-Gi/o alpha fusion proteins
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	A1 and A3 receptors bind adenosine
orthologousEvent	[Reaction:R-CEL-418904] A1 and A3 receptors bind adenosine - Caenorhabditis elegans [Reaction:R-DME-418904] A1 and A3 receptors bind adenosine - Drosophila melanogaster [Reaction:R-GGA-418904] A1 and A3 receptors bind adenosine - Gallus gallus [Reaction:R-DRE-418904] A1 and A3 receptors bind adenosine - Danio rerio [Reaction:R-SSC-418904] A1 and A3 receptors bind adenosine - Sus scrofa [Reaction:R-BTA-418904] A1 and A3 receptors bind adenosine - Bos taurus [Reaction:R-CFA-418904] A1 and A3 receptors bind adenosine - Canis familiaris [Reaction:R-RNO-418904] A1 and A3 receptors bind adenosine - Rattus norvegicus [Reaction:R-MMU-418904] A1 and A3 receptors bind adenosine - Mus musculus
output	[Complex:R-HSA-418897] ADORA1,3:Ade-Rib [plasma membrane]
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:422381] D'Eustachio, P, 2009-05-29 07:44:22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-418904
summation	[Summation:418940] The A1 receptor (Libert F et al, 1992) has an inhibitory fun...

Referrals

(hasEvent)	[Pathway:R-HSA-417973] Adenosine P1 receptors
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi