Reactome | Cytosolic Neu5Ac translocates to nucleus

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Cytosolic Neu5Ac translocates to nucleus Show undefined attributes

authored	[InstanceEdit:4085031] Jassal, Bijay, 2013-08-01
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:4085031] Jassal, Bijay, 2013-08-01
crossReference	[DatabaseIdentifier:12667596] RHEA:28991 [DatabaseIdentifier:9974420] RHEA:28991
dbId	4085020
displayName	Cytosolic Neu5Ac translocates to nucleus
edited	[InstanceEdit:4085031] Jassal, Bijay, 2013-08-01
eventOf	[Pathway:R-HSA-4085001] Sialic acid metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-4084982] CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac - Homo sapiens
input	[SimpleEntity:R-ALL-428633] Neu5Ac [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4088193] Sialic acid metabolism and sialyltransferases: natural functions and applications
maxDepth	1
modified	[InstanceEdit:9974412] D'Eustachio, Peter, 2025-11-21
name	Cytosolic Neu5Ac translocates to nucleus N-acetylneuraminate(in) = N-acetylneuraminate(out)
output	[SimpleEntity:R-ALL-4085414] Neu5Ac [nucleoplasm]
precedingEvent	[Reaction:R-HSA-4084989] NANP dephosphorylates Neu5Ac-9-P to Neu5Ac - Homo sapiens [Reaction:R-HSA-4085029] NEU2 hydrolyzes Neu5Ac from glycoconjugates - Homo sapiens [Reaction:R-HSA-4084994] NEU3 hydrolyzes Neu5Ac from glycoconjugates - Homo sapiens [Reaction:R-HSA-428585] SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol - Homo sapiens
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5225590] Medrano, Juan F, Wickramasinghe, Saumya, 2014-01-08
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-4085020
summation	[Summation:4085434] N-acetylneuraminate (Neu5Ac) translocates to the nucleus thr...

Referrals

(hasEvent)	[Pathway:R-HSA-4085001] Sialic acid metabolism
(precedingEvent)	[Reaction:R-HSA-4084982] CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac

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