Reactome | PLC beta is activated by G alpha (q)

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PLC beta is activated by G alpha (q) Show undefined attributes

authored	[InstanceEdit:425206] Jupe, S, 2009-06-03
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:398187] Jupe, S, 2009-03-18 10:29:36
dbId	398188
displayName	PLC beta is activated by G alpha (q)
edited	[InstanceEdit:435382] Jupe, S, 2009-09-09
eventOf	[Pathway:R-HSA-416476] G alpha (q) signalling events - Homo sapiens
inferredFrom	[Reaction:R-BTA-374858] Activation of PLC beta-1 - Bos taurus
input	[Complex:R-HSA-114534] G-protein alpha (q/11): GTP [plasma membrane] [DefinedSet:R-HSA-111854] PLC-beta [cytosol]
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:398020] A unique fold of phospholipase C-beta mediates dimerization and interaction with G alpha q [LiteratureReference:398022] Cell signalling diversity of the Gqalpha family of heterotrimeric G proteins
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PLC beta is activated by G alpha (q)
output	[Complex:R-HSA-398158] PLC beta:G alpha (q/11) [plasma membrane]
precedingEvent	[Reaction:R-HSA-418576] Dissociation of the P2Y purinoceptor 1:Gq complex - Homo sapiens [Reaction:R-HSA-397835] Thrombin-activated PARs:Gq (active) dissociate - Homo sapiens [Reaction:R-HSA-428752] Dissociation of the TP:Gq complex - Homo sapiens [Reaction:R-HSA-749452] The Ligand:GPCR:Gq complex dissociates - Homo sapiens
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
revised	[InstanceEdit:9012014] Varusai, Thawfeek, 2017-07-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-398188
summation	[Summation:374856] The active form of G protein alpha subunit q (Gq-alpha) was ...
updateTrackers	[UpdateTracker:9790433] Update Tracker - [Reaction:398188] PLC beta is activated by G alpha (q) - v33:[add_removeInput] [UpdateTracker:9791189] Update Tracker - [Reaction:398188] PLC beta is activated by G alpha (q) - v32:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9790433] Update Tracker - [Reaction:398188] PLC beta is activated by G alpha (q) - v33:[add_removeInput] [UpdateTracker:9791189] Update Tracker - [Reaction:398188] PLC beta is activated by G alpha (q) - v32:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-416476] G alpha (q) signalling events
(inferredTo)	[Reaction:R-BTA-374858] Activation of PLC beta-1