Reactome | Gs activation by prostacyclin receptor

Schema > Reaction > Entries

Gs activation by prostacyclin receptor Show undefined attributes

authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:432083] guanyl-nucleotide exchange factor activity of Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:392869] Jupe, S, 2009-03-09 15:01:27
dbId	392870
displayName	Gs activation by prostacyclin receptor
edited	[InstanceEdit:870305] Jupe, S, 2010-06-07
eventOf	[Pathway:R-HSA-392851] Prostacyclin signalling through prostacyclin receptor - Homo sapiens
followingEvent	[Reaction:R-HSA-392874] Dissociation of the Prostacyclin receptor:Gs complex - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-HSA-392864] Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:421925] Can a GDP-liganded G-protein be active?
modified	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
name	Gs activation by prostacyclin receptor
orthologousEvent	[Reaction:R-DME-392870] Gs activation by prostacyclin receptor - Drosophila melanogaster [Reaction:R-XTR-392870] Gs activation by prostacyclin receptor - Xenopus tropicalis [Reaction:R-SSC-392870] Gs activation by prostacyclin receptor - Sus scrofa [Reaction:R-BTA-392870] Gs activation by prostacyclin receptor - Bos taurus [Reaction:R-CFA-392870] Gs activation by prostacyclin receptor - Canis familiaris [Reaction:R-MMU-392870] Gs activation by prostacyclin receptor - Mus musculus
output	[SimpleEntity:R-ALL-114549] GDP [plasma membrane] [Complex:R-HSA-392865] Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane]
precedingEvent	[Reaction:R-HSA-392852] Activated prostacyclin receptor binds G-protein Gs - Homo sapiens
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-392870
summation	[Summation:391991] The G-protein alpha subunit exchanges GDP for GTP

Referrals

(hasEvent)	[Pathway:R-HSA-392851] Prostacyclin signalling through prostacyclin receptor
(precedingEvent)	[Reaction:R-HSA-392874] Dissociation of the Prostacyclin receptor:Gs complex