Reactome | Activated prostacyclin receptor binds G-protein Gs

Schema > Reaction > Entries

authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:392853] Jupe, S, 2009-03-09 13:56:27
dbId	392852
displayName	Activated prostacyclin receptor binds G-protein Gs
edited	[InstanceEdit:870305] Jupe, S, 2010-06-07
eventOf	[Pathway:R-HSA-392851] Prostacyclin signalling through prostacyclin receptor - Homo sapiens
followingEvent	[Reaction:R-HSA-392870] Gs activation by prostacyclin receptor - Homo sapiens
input	[Complex:R-HSA-391179] Heterotrimeric G-protein Gs (inactive) [plasma membrane] [Complex:R-HSA-391929] PTGIR:PGI2 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:400652] Solution structure of the first intracellular loop of prostacyclin receptor and implication of its interaction with the C-terminal segment of G alpha s protein
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activated prostacyclin receptor binds G-protein Gs
output	[Complex:R-HSA-392864] Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
precedingEvent	[Reaction:R-HSA-391942] IP receptor can bind prostacyclin - Homo sapiens
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-392852
summation	[Summation:400654] The human prostacyclin receptor (IP) and G-protein alpha (s)...

(hasEvent)	[Pathway:R-HSA-392851] Prostacyclin signalling through prostacyclin receptor
(precedingEvent)	[Reaction:R-HSA-392870] Gs activation by prostacyclin receptor

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