Reactome | Proteinase-activated receptors can bind thrombin

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Proteinase-activated receptors can bind thrombin Show undefined attributes

authored	[InstanceEdit:389485] Jassal, B, 2009-01-07 14:37:24
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:389485] Jassal, B, 2009-01-07 14:37:24
dbId	389463
displayName	Proteinase-activated receptors can bind thrombin
edited	[InstanceEdit:389485] Jassal, B, 2009-01-07 14:37:24
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
input	[Complex:R-HSA-156786] activated thrombin (factor IIa) [extracellular region] [DefinedSet:R-HSA-389458] Proteinase-activated receptors [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:140590] Primary structure of human prethrombin 2 and alpha-thrombin [LiteratureReference:389499] Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin [LiteratureReference:389466] Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Proteinase-activated receptors can bind thrombin
orthologousEvent	[Reaction:R-GGA-389463] Proteinase-activated receptors can bind thrombin - Gallus gallus [Reaction:R-XTR-389463] Proteinase-activated receptors can bind thrombin - Xenopus tropicalis [Reaction:R-DRE-389463] Proteinase-activated receptors can bind thrombin - Danio rerio [Reaction:R-SSC-389463] Proteinase-activated receptors can bind thrombin - Sus scrofa [Reaction:R-BTA-389463] Proteinase-activated receptors can bind thrombin - Bos taurus [Reaction:R-CFA-389463] Proteinase-activated receptors can bind thrombin - Canis familiaris [Reaction:R-RNO-389463] Proteinase-activated receptors can bind thrombin - Rattus norvegicus [Reaction:R-MMU-389463] Proteinase-activated receptors can bind thrombin - Mus musculus
output	[Complex:R-HSA-389470] Thrombin:Proteinase-activated receptors [plasma membrane]
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392262] D'Eustachio, P, 2009-03-02 09:24:35
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-389463
summation	[Summation:389401] Thrombin (Butkowski RJ et al, 1977) plays a vital role in bl...

Referrals

(hasEvent)

[Pathway:R-HSA-375276] Peptide ligand-binding receptors