Reactome | Extracellular processing of novel PDGFs

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Extracellular processing of novel PDGFs Show undefined attributes

authored	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
catalystActivity	[CatalystActivity:382059] serine-type endopeptidase activity of serine-type endopeptidases involved in novel PDGF processing [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:382060] Garapati, P V, 2008-11-21 20:21:25
dbId	382061
displayName	Extracellular processing of novel PDGFs
edited	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
eventOf	[Pathway:R-HSA-186797] Signaling by PDGF - Homo sapiens
input	[DefinedSet:R-HSA-381947] Novel PDGF precursor dimers (CC, DD) [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:380726] The PDGF family: four gene products form five dimeric isoforms
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Extracellular processing of novel PDGFs
orthologousEvent	[Reaction:R-CEL-382061] Extracellular processing of novel PDGFs - Caenorhabditis elegans [Reaction:R-GGA-382061] Extracellular processing of novel PDGFs - Gallus gallus [Reaction:R-XTR-382061] Extracellular processing of novel PDGFs - Xenopus tropicalis [Reaction:R-DRE-382061] Extracellular processing of novel PDGFs - Danio rerio [Reaction:R-SSC-382061] Extracellular processing of novel PDGFs - Sus scrofa [Reaction:R-BTA-382061] Extracellular processing of novel PDGFs - Bos taurus [Reaction:R-CFA-382061] Extracellular processing of novel PDGFs - Canis familiaris [Reaction:R-RNO-382061] Extracellular processing of novel PDGFs - Rattus norvegicus [Reaction:R-MMU-382061] Extracellular processing of novel PDGFs - Mus musculus
output	[DefinedSet:R-HSA-381939] Active PDGF dimers (CC, DD) [extracellular region] 2 × [DefinedSet:R-HSA-389070] Cleaved novel PDGF fragments [extracellular region]
precedingEvent	[BlackBoxEvent:R-HSA-382057] Release of novel PDGFs as latent factors - Homo sapiens
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:382617] Heldin, CH, 2008-11-23 19:29:34
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-382061
summation	[Summation:381884] During the extracellular proteolytic activation of PDGF-C an...

Referrals

(hasEvent)

[Pathway:R-HSA-186797] Signaling by PDGF