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Schema
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Reaction
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Entries
Reuptake of serotonin from the synapse
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authored
[InstanceEdit:379392] Mahajan, SS, 2008-10-17 21:22:50
catalystActivity
[CatalystActivity:380614] monoamine transmembrane transporter activity of SLC6A4 [plasma membrane]
category
transition
compartment
[Compartment:984] extracellular region
[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created
[InstanceEdit:380609] Mahajan, SS, 2008-11-13 15:40:08
dbId
380620
displayName
Reuptake of serotonin from the synapse
edited
[InstanceEdit:447013] Gillespie, ME, 2009-11-19
eventOf
[Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters - Homo sapiens
input
[SimpleEntity:R-ALL-114523] 5HT [extracellular region]
[SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:380897] Long story short: the serotonin transporter in emotion regulation and social cognition
maxDepth
1
modified
[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
Reuptake of serotonin from the synapse
orthologousEvent
[Reaction:R-PFA-380620] Reuptake of serotonin from the synapse - Plasmodium falciparum
[Reaction:R-CEL-380620] Reuptake of serotonin from the synapse - Caenorhabditis elegans
[Reaction:R-DME-380620] Reuptake of serotonin from the synapse - Drosophila melanogaster
[Reaction:R-GGA-380620] Reuptake of serotonin from the synapse - Gallus gallus
[Reaction:R-XTR-380620] Reuptake of serotonin from the synapse - Xenopus tropicalis
[Reaction:R-DRE-380620] Reuptake of serotonin from the synapse - Danio rerio
[Reaction:R-SSC-380620] Reuptake of serotonin from the synapse - Sus scrofa
[Reaction:R-BTA-380620] Reuptake of serotonin from the synapse - Bos taurus
[Reaction:R-CFA-380620] Reuptake of serotonin from the synapse - Canis familiaris
[Reaction:R-RNO-380620] Reuptake of serotonin from the synapse - Rattus norvegicus
[Reaction:R-MMU-380620] Reuptake of serotonin from the synapse - Mus musculus
output
[SimpleEntity:R-ALL-209914] 5HT [cytosol]
[SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate
2008-12-17
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:386898] Restituito, S, 2008-11-27 12:38:49
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-380620
summation
[Summation:380610] The human gene SLC6A4 encodes the sodium-dependent serotonin...
updateTrackers
[UpdateTracker:9791397] Update Tracker - [Reaction:380620] Reuptake of serotonin from the synapse - v30:[add_removeInput]
[UpdateTracker:9791337] Update Tracker - [Reaction:380620] Reuptake of serotonin from the synapse - v31:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9791397] Update Tracker - [Reaction:380620] Reuptake of serotonin from the synapse - v30:[add_removeInput]
[UpdateTracker:9791337] Update Tracker - [Reaction:380620] Reuptake of serotonin from the synapse - v31:[modifyText]
(hasEvent)
[Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters
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