Reactome | Opioid receptors bind opioid peptides

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Opioid receptors bind opioid peptides Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:374275] Jassal, Bijay, 2008-07-29
dbId	374298
displayName	Opioid receptors bind opioid peptides
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[DefinedSet:R-HSA-374370] Opioid ligands [extracellular region] [DefinedSet:R-HSA-374277] Opioid receptors [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:374289] Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA [LiteratureReference:374270] Isolation and structural organization of the human preproenkephalin gene [LiteratureReference:374276] Identification of a human delta opioid receptor: cloning and expression [LiteratureReference:374101] Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment [LiteratureReference:374296] kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Opioid receptors bind opioid peptides
orthologousEvent	[Reaction:R-GGA-374298] Opioid receptors bind opioid peptides - Gallus gallus [Reaction:R-XTR-374298] Opioid receptors bind opioid peptides - Xenopus tropicalis [Reaction:R-DRE-374298] Opioid receptors bind opioid peptides - Danio rerio [Reaction:R-SSC-374298] Opioid receptors bind opioid peptides - Sus scrofa [Reaction:R-BTA-374298] Opioid receptors bind opioid peptides - Bos taurus [Reaction:R-CFA-374298] Opioid receptors bind opioid peptides - Canis familiaris [Reaction:R-RNO-374298] Opioid receptors bind opioid peptides - Rattus norvegicus [Reaction:R-MMU-374298] Opioid receptors bind opioid peptides - Mus musculus
output	[Complex:R-HSA-374302] Opioid receptor:opioid ligand [plasma membrane]
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-374298
summation	[Summation:374290] There are three well-characterized families of opioid peptid...

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(hasEvent)	[Pathway:R-HSA-375276] Peptide ligand-binding receptors
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi