Reactome | Receptor CCR6 binds CCL20 ligand

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Receptor CCR6 binds CCL20 ligand Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:373072] Jassal, Bijay, 2008-07-14
dbId	373087
displayName	Receptor CCR6 binds CCL20 ligand
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-380108] Chemokine receptors bind chemokines - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-373097] CCL20(27-96) [extracellular region] [EntityWithAccessionedSequence:R-HSA-373089] CCR6 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:373245] Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC [LiteratureReference:373254] The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Receptor CCR6 binds CCL20 ligand
orthologousEvent	[Reaction:R-GGA-373087] Receptor CCR6 binds CCL20 ligand - Gallus gallus [Reaction:R-DRE-373087] Receptor CCR6 binds CCL20 ligand - Danio rerio [Reaction:R-SSC-373087] Receptor CCR6 binds CCL20 ligand - Sus scrofa [Reaction:R-BTA-373087] Receptor CCR6 binds CCL20 ligand - Bos taurus [Reaction:R-RNO-373087] Receptor CCR6 binds CCL20 ligand - Rattus norvegicus [Reaction:R-MMU-373087] Receptor CCR6 binds CCL20 ligand - Mus musculus
output	[Complex:R-HSA-373235] CCR6:CCL20 [plasma membrane]
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-373087
summation	[Summation:373269] CCR6 (Baba M et al, 1997) is expressed on inactive memory T-...

Referrals

(hasEvent)	[Pathway:R-HSA-380108] Chemokine receptors bind chemokines
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi