CCR6 (Baba M et al, 1997) is expressed on inactive memory T-cells and on Th17 cells. CCR6 is down-regulated in activated T-cells. CCL20 (macrophage inflammatory protein 3-alpha, MIP 3-alpha) binds and activates CCR6 and it does not share the binding site of CCR6 with any other chemokine.
Yoshie, O, Nishimura, M, Takagi, S, Hieshima, K, Baba, M, Kakizaki, M, Nomiyama, H, Imai, T
Lubkowski, J, Boulegue, C, Hoover, DM, Oppenheim, JJ, Yang, D, Tucker, K, Lu, W
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