Reactome | Interaction of integrin alphaIIb beta3 with Fibrinogen

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Interaction of integrin alphaIIb beta3 with Fibrinogen Show undefined attributes

authored	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
dbId	354149
displayName	Interaction of integrin alphaIIb beta3 with Fibrinogen
edited	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
eventOf	[Pathway:R-HSA-354192] Integrin signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-377641] Clustering of Integrin alphaIIb beta3 complexes - Homo sapiens
input	[DefinedSet:R-HSA-377603] Integrin alphaIIb beta3 ECM ligands [extracellular region] [Complex:R-HSA-354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] [CandidateSet:R-ALL-377604] Integrin binding divalent cations [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:354175] Integrin activation [LiteratureReference:354127] Integrin signaling [LiteratureReference:349611] Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 detected using force spectroscopy
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Interaction of integrin alphaIIb beta3 with Fibrinogen
orthologousEvent	[Reaction:R-CEL-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Caenorhabditis elegans [Reaction:R-GGA-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Gallus gallus [Reaction:R-XTR-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Xenopus tropicalis [Reaction:R-DRE-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Danio rerio [Reaction:R-SSC-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Sus scrofa [Reaction:R-BTA-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Bos taurus [Reaction:R-CFA-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Canis familiaris [Reaction:R-RNO-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Rattus norvegicus [Reaction:R-MMU-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Mus musculus
output	[Complex:R-HSA-354137] Focal complex [plasma membrane]
precedingEvent	[Reaction:R-HSA-354077] Integrin alphaIIb beta3 activation - Homo sapiens
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-354149
summation	[Summation:354108] The overall shape of integrins is that of a globular 'head' ...
updateTrackers	[UpdateTracker:9790215] Update Tracker - [Reaction:354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - v34:[modifyText] [UpdateTracker:9789961] Update Tracker - [Reaction:354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - v36:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9790215] Update Tracker - [Reaction:354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - v34:[modifyText] [UpdateTracker:9789961] Update Tracker - [Reaction:354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - v36:[addLiteratureReference, modifyText]
(precedingEvent)	[Reaction:R-HSA-377641] Clustering of Integrin alphaIIb beta3 complexes
(hasEvent)	[Pathway:R-HSA-354192] Integrin signaling

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