Reactome | Interaction of integrin alphaIIb beta3 with Fibrinogen

Schema > Reaction > Entries

Interaction of integrin alphaIIb beta3 with Fibrinogen Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10752103
displayName	Interaction of integrin alphaIIb beta3 with Fibrinogen
eventOf	[Pathway:R-GGA-354192] Integrin signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-377641] Clustering of Integrin alphaIIb beta3 complexes - Gallus gallus
inferredFrom	[Reaction:R-HSA-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Homo sapiens
input	[DefinedSet:R-GGA-377603] Integrin alphaIIb beta3 ECM ligands [extracellular region] [Complex:R-GGA-354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] [CandidateSet:R-ALL-377604] Integrin binding divalent cations [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of integrin alphaIIb beta3 with Fibrinogen
output	[Complex:R-GGA-354137] Focal complex [plasma membrane]
precedingEvent	[Reaction:R-GGA-354077] Integrin alphaIIb beta3 activation - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-354149
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-354192] Integrin signaling
(precedingEvent)	[Reaction:R-GGA-377641] Clustering of Integrin alphaIIb beta3 complexes
(inferredTo)	[Reaction:R-HSA-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen

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