Reactome | SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol

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SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:352055] amino acid transmembrane transporter activity of SLC6A20 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352063] D'Eustachio, P, 2008-05-30 00:13:57
crossReference	[DatabaseIdentifier:12667961] RHEA:28967
dbId	352052
diseaseReaction	[FailedReaction:R-HSA-5660694] Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol - Homo sapiens
displayName	SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
eventOf	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens
input	[SimpleEntity:R-ALL-352033] L-Pro [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:352054] Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol
orthologousEvent	[Reaction:R-PFA-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Plasmodium falciparum [Reaction:R-DME-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Drosophila melanogaster [Reaction:R-GGA-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Gallus gallus [Reaction:R-XTR-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Xenopus tropicalis [Reaction:R-SSC-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Bos taurus [Reaction:R-CFA-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Mus musculus
output	[SimpleEntity:R-ALL-113538] L-Pro [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-352052
summation	[Summation:352046] SLC6A20, associated with the plasma membrane, mediates the u...

Referrals

(normalReaction)	[FailedReaction:R-HSA-5660694] Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol
(hasEvent)	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane [Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters