SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol

Stable Identifier
R-HSA-352052
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol
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SLC6A20, associated with the plasma membrane, mediates the uptake of proline plus a sodium ion. The human protein is expressed in the intestine and kidney (Takanaga et al. 2005).
Literature References
PubMed ID Title Journal Year
15632147 Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino

Mackenzie, B, Takanaga, H, Hediger, MA, Suzuki, Y

J Biol Chem 2005
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Output
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as an event of
Catalyst Activity

amino acid transmembrane transporter activity of SLC6A20 [plasma membrane]

Physical Entity
SLC6A20 [plasma membrane] (Homo sapiens)
Activity
amino acid transmembrane transporter activity (GO:0015171)
Orthologous Events
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Bos taurus)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Canis familiaris)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Drosophila melanogaster)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Gallus gallus)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Mus musculus)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Plasmodium falciparum)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Rattus norvegicus)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Sus scrofa)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Xenopus tropicalis)
Cross References
Rhea
Authored
D'Eustachio, P  (2008-06-03)
Reviewed
Jassal, B  (2008-06-03)
Created
D'Eustachio, P  (2008-05-30)
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