Reactome | Apoptotic cleavage of cell adhesion proteins

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Apoptotic cleavage of cell adhesion proteins Show undefined attributes

authored	[InstanceEdit:352235] Schulze-Osthoff, K, 2008-05-18 10:00:05
created	[InstanceEdit:351919] Matthews, L, 2008-05-28 22:38:42
dbId	351906
displayName	Apoptotic cleavage of cell adhesion proteins
edited	[InstanceEdit:353176] Matthews, L, 2008-06-12 00:23:53
eventOf	[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-202939] Caspase-mediated cleavage of E-Cadherin - Homo sapiens [Reaction:R-HSA-202969] Caspase mediated cleavage of beta-catenin - Homo sapiens [Reaction:R-HSA-201631] Caspase-mediated cleavage of Desmoglein 3 - Homo sapiens [Reaction:R-HSA-351877] Caspase-mediated cleavage of Desmoglein 2 - Homo sapiens [Reaction:R-HSA-202917] Caspase-mediated cleavage of Desmoglein 1 - Homo sapiens [Reaction:R-HSA-201636] Caspase-mediated cleavage of Desmoplakin - Homo sapiens [Reaction:R-HSA-201595] Caspase-mediated cleavage of plakophilin-1 - Homo sapiens [Reaction:R-HSA-351913] Caspase-mediated cleavage of TJP1 - Homo sapiens [Reaction:R-HSA-351871] Caspase-mediated cleavage of Z0-2 - Homo sapiens [Reaction:R-HSA-351876] Caspase-mediated cleavage of occludin - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-03-26
literatureReference	[LiteratureReference:202907] The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes [LiteratureReference:202796] The fate of desmosomal proteins in apoptotic cells [LiteratureReference:351838] The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery
maxDepth	2
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Apoptotic cleavage of cell adhesion proteins
orthologousEvent	[Pathway:R-DME-351906] Apoptotic cleavage of cell adhesion proteins - Drosophila melanogaster [Pathway:R-GGA-351906] Apoptotic cleavage of cell adhesion proteins - Gallus gallus [Pathway:R-XTR-351906] Apoptotic cleavage of cell adhesion proteins - Xenopus tropicalis [Pathway:R-DRE-351906] Apoptotic cleavage of cell adhesion proteins - Danio rerio [Pathway:R-SSC-351906] Apoptotic cleavage of cell adhesion proteins - Sus scrofa [Pathway:R-BTA-351906] Apoptotic cleavage of cell adhesion proteins - Bos taurus [Pathway:R-CFA-351906] Apoptotic cleavage of cell adhesion proteins - Canis familiaris [Pathway:R-RNO-351906] Apoptotic cleavage of cell adhesion proteins - Rattus norvegicus [Pathway:R-MMU-351906] Apoptotic cleavage of cell adhesion proteins - Mus musculus
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:350641] Ranganathan, S, 2008-06-11 19:13:33
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-351906
summation	[Summation:351833] Apoptotic cells show dramatic rearrangements of tight junct...
updateTrackers	[UpdateTracker:9787411] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v45:[updateContainedRLE] [UpdateTracker:9791630] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v28:[updateContainedRLE] [UpdateTracker:9780136] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v64:[updateContainedRLE] [UpdateTracker:9786961] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v46:[updateContainedRLE] [UpdateTracker:9791077] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v32:[updateContainedRLE]

Referrals

(updatedInstance)

[UpdateTracker:9787411] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v45:[updateContainedRLE]
[UpdateTracker:9791630] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v28:[updateContainedRLE]
[UpdateTracker:9780136] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v64:[updateContainedRLE]
[UpdateTracker:9786961] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v46:[updateContainedRLE]
[UpdateTracker:9791077] Update Tracker - [Pathway:351906] Apoptotic cleavage of cell adhesion proteins - v32:[updateContainedRLE]

(hasEvent)

[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins

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