Reactome | Caspase-mediated cleavage of MST3

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Caspase-mediated cleavage of MST3 Show undefined attributes

authored	[InstanceEdit:352235] Schulze-Osthoff, K, 2008-05-18 10:00:05
catalystActivity	[CatalystActivity:202853] cysteine-type endopeptidase activity of Caspase-3, Caspase-7 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:351919] Matthews, L, 2008-05-28 22:38:42
dbId	351901
displayName	Caspase-mediated cleavage of MST3
edited	[InstanceEdit:351852] Matthews, L, 2008-05-27 07:43:39
eventOf	[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins - Homo sapiens
followingEvent	[Reaction:R-HSA-351947] Nuclear translocation of catalytic domain of Mst3 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-351829] STK24 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:351841] Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis [LiteratureReference:9029657] An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Caspase-mediated cleavage of MST3
orthologousEvent	[Reaction:R-DME-351901] Caspase-mediated cleavage of MST3 - Drosophila melanogaster [Reaction:R-GGA-351901] Caspase-mediated cleavage of MST3 - Gallus gallus [Reaction:R-XTR-351901] Caspase-mediated cleavage of MST3 - Xenopus tropicalis [Reaction:R-DRE-351901] Caspase-mediated cleavage of MST3 - Danio rerio [Reaction:R-SSC-351901] Caspase-mediated cleavage of MST3 - Sus scrofa [Reaction:R-BTA-351901] Caspase-mediated cleavage of MST3 - Bos taurus [Reaction:R-CFA-351901] Caspase-mediated cleavage of MST3 - Canis familiaris [Reaction:R-RNO-351901] Caspase-mediated cleavage of MST3 - Rattus norvegicus [Reaction:R-MMU-351901] Caspase-mediated cleavage of MST3 - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-351892] STK24(1-325) [cytosol] [EntityWithAccessionedSequence:R-HSA-351898] STK24(326-443) [cytosol]
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:350641] Ranganathan, S, 2008-06-11 19:13:33
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-351901
summation	[Summation:351867] Caspase-mediated cleavage of Mst3 activates its intrinsic ki...
updateTrackers	[UpdateTracker:9780004] Update Tracker - [Reaction:351901] Caspase-mediated cleavage of MST3 - v64:[addLiteratureReference, add_removeCatalystActivity, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780004] Update Tracker - [Reaction:351901] Caspase-mediated cleavage of MST3 - v64:[addLiteratureReference, add_removeCatalystActivity, modifyText]
(precedingEvent)	[Reaction:R-HSA-351947] Nuclear translocation of catalytic domain of Mst3
(hasEvent)	[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins