Reactome | ERF inhibits ETS2 expression

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ERF inhibits ETS2 expression Show undefined attributes

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3209180] Orlic-Milacic, M, 2013-03-01
dbId	3209179
displayName	ERF inhibits ETS2 expression
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
eventOf	[Pathway:R-HSA-2559585] Oncogene Induced Senescence - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3209178] ETS2 Gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3209175] ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERF inhibits ETS2 expression
output	[EntityWithAccessionedSequence:R-HSA-1629811] ETS2 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-3209177] ERF binds ETS2 promoter - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:R-HSA-3209181] Negative gene expression regulation by 'ERF:ETS2 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642650] Negative gene expression regulation by 'ERF:ETS2 Gene [nucleoplasm]' ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-3209179
summation	[Summation:3245933] Binding of ERF to ETS2 promoter strongly represses ETS2 tran...

Referrals

(hasEvent)

[Pathway:R-HSA-2559585] Oncogene Induced Senescence