Reactome | Translation of p14ARF mRNA is inhibited by miR-24

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Translation of p14ARF mRNA is inhibited by miR-24 Show undefined attributes

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3209104] Orlic-Milacic, M, 2013-03-01
dbId	3209111
displayName	Translation of p14ARF mRNA is inhibited by miR-24
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
eventOf	[Pathway:R-HSA-2559585] Oncogene Induced Senescence - Homo sapiens [Pathway:R-HSA-2559580] Oxidative Stress Induced Senescence - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9645672] p14ARF translocates to the nucleus - Homo sapiens [Reaction:R-HSA-9645694] p14ARF binds C1QBP - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3209107] p14ARF mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3209136] Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translation of p14ARF mRNA is inhibited by miR-24
output	[EntityWithAccessionedSequence:R-HSA-9645669] p14ARF [cytosol]
precedingEvent	[Reaction:R-HSA-3209151] miR-24 binds p16INK4A and p14ARF mRNAs - Homo sapiens
regulatedBy	[NegativeRegulation:R-HSA-3209125] Negative regulation by 'p16INK4A/p14ARF mRNA: miR-24 Nonendonucleolytic RISC [cytosol]'
regulationReference	[RegulationReference:9642592] Negative regulation by 'p16-INK4a/p14-ARF mRNA: miR-24 Nonendonucleolytic RISC [cytosol]' Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-3209111
summation	[Summation:3245955] MicroRNA miR-24 inhibits translation of p14ARF mRNA without ...
updateTrackers	[UpdateTracker:9777747] Update Tracker - [BlackBoxEvent:3209111] Translation of p14ARF mRNA is inhibited by miR-24 - v69:[modifyText] [UpdateTracker:9777628] Update Tracker - [BlackBoxEvent:3209111] Translation of p14ARF mRNA is inhibited by miR-24 - v70:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9777747] Update Tracker - [BlackBoxEvent:3209111] Translation of p14ARF mRNA is inhibited by miR-24 - v69:[modifyText] [UpdateTracker:9777628] Update Tracker - [BlackBoxEvent:3209111] Translation of p14ARF mRNA is inhibited by miR-24 - v70:[add_removeOutput]
(hasEvent)	[Pathway:R-HSA-2559580] Oxidative Stress Induced Senescence [Pathway:R-HSA-2559585] Oncogene Induced Senescence
(precedingEvent)	[BlackBoxEvent:R-HSA-9645672] p14ARF translocates to the nucleus [Reaction:R-HSA-9645694] p14ARF binds C1QBP