Translation of p14ARF mRNA is inhibited by miR-24

Stable Identifier
R-HSA-3209111
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
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Translation of p14ARF mRNA is inhibited by miR-24
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MicroRNA miR-24 inhibits translation of p14ARF mRNA without causing mRNA degradation. This results in high p14ARF transcript level accompanied by low p14ARF protein level (To et al. 2012).

Literature References
PubMed ID Title Journal Year
22336108 Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development

Thériault, BL, Gallie, BL, To, KH, Pajovic, S

BMC Cancer 2012
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Output
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as an event of
This event is regulated
Negatively by
Regulator
p16INK4A/p14ARF mRNA: miR-24 Nonendonucleolytic RISC [cytosol] (Homo sapiens)
Active Unit
miR-24 Nonendonucleolytic RISC [cytosol]
Authored
Orlic-Milacic, M  (2013-07-15)
Reviewed
Samarajiwa, S  (2013-09-03)
Created
Orlic-Milacic, M  (2013-03-01)
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