Reactome | NRP1 [plasma membrane]

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-374580] L1:NRP1 [plasma membrane] - Homo sapiens [Complex:R-HSA-399841] NRP1:Plexin-A1-4:FYN [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-374669] L1 binds NRP1 - Homo sapiens [Reaction:R-HSA-445083] CHL1 interacts with NRP1 - Homo sapiens [Reaction:R-HSA-9010951] ROBO1 binds NRP1 - Homo sapiens [Reaction:R-HSA-195408] NRP-1 forms a ternary complex with VEGF165 and VEGFR1 - Homo sapiens [Reaction:R-HSA-195408] NRP-1 forms a ternary complex with VEGF165 and VEGFR1 - Homo sapiens [Reaction:R-HSA-399942] Plexin-A1-4 binds NRP1 - Homo sapiens
created	[InstanceEdit:3008772] Jupe, S, 2013-02-01
dbId	3008773
displayName	NRP1 [plasma membrane]
endCoordinate	923
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-421085] Nrp1 [plasma membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-3008773] NRP1 [plasma membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-3008773] NRP1 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-3008773] NRP1 [plasma membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-3008773] NRP1 [plasma membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-3008773] NRP1 [plasma membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-3008773] NRP1 [plasma membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-3008773] NRP1 [plasma membrane] - Gallus gallus [GenomeEncodedEntity:R-CEL-3008773] Ghost homologue of NRP1 [plasma membrane] - Caenorhabditis elegans
maxDepth	1
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	NRP1 Neuropilin-1 NRP1_HUMAN
positivelyRegulates	[PositiveRegulation:9768874] Positive regulation by 'NRP1 [plasma membrane]'
referenceEntity	[ReferenceGeneProduct:uniprot:O14786] UniProt:O14786 NRP1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3008773
startCoordinate	22

(hasComponent)	[Complex:R-HSA-374580] L1:NRP1 [plasma membrane] [Complex:R-HSA-445017] CHL1:NRP1 [plasma membrane] [Complex:R-HSA-9010959] ROBO1:NRP1 [plasma membrane] [Complex:R-HSA-195419] NRP1:VEGFR2 dimer [plasma membrane] [Complex:R-HSA-399841] NRP1:Plexin-A1-4:FYN [plasma membrane] [Complex:R-HSA-399837] NRP1:PlexinA1-4:FARP2:FYN [plasma membrane] [Complex:R-HSA-399846] NRP1:PlexinA1-4:FYN [plasma membrane] [Complex:R-HSA-399845] NRP1:PlexinA1-4:FYN:pCdk5:p53 [plasma membrane] [Complex:R-HSA-399853] Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's (S522,S518,T509,T514) [plasma membrane] [Complex:R-HSA-399855] NRP1:PlexinA1-4:FYN:Cdk5:p53:p-CRMP tetramers [plasma membrane] [Complex:R-HSA-419625] NRP1:p-Plexin-A1-4:FYN [plasma membrane]
(input)	[Reaction:R-HSA-374669] L1 binds NRP1 [Reaction:R-HSA-445083] CHL1 interacts with NRP1 [Reaction:R-HSA-9010951] ROBO1 binds NRP1 [Reaction:R-HSA-195408] NRP-1 forms a ternary complex with VEGF165 and VEGFR1 [Reaction:R-HSA-399942] Plexin-A1-4 binds NRP1
(regulator)	[PositiveRegulation:9768874] Positive regulation by 'NRP1 [plasma membrane]'

NRP1 [plasma membrane] Show undefined attributes

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