Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Reaction
>
Entries
POU5F1 (OCT4), SOX2, NANOG Bind the SALL1 Promoter
Show undefined attributes
Go to Details
authored
[InstanceEdit:2901807] May, B, 2013-01-03
category
binding
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:2972945] D'Eustachio, P, 2013-01-06
dbId
2972975
displayName
POU5F1 (OCT4), SOX2, NANOG Bind the SALL1 Promoter
edited
[InstanceEdit:2901807] May, B, 2013-01-03
eventOf
[Pathway:R-HSA-2892247] POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation - Homo sapiens
followingEvent
[BlackBoxEvent:R-HSA-452958] Expression of SALL1 - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-452586] NANOG [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-452472] POU5F1 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-2888989] SALL1 gene [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-452271] SOX2 [nucleoplasm]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells
[LiteratureReference:452628] Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
[LiteratureReference:2972938] Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development
[LiteratureReference:994184] A novel SALL4/OCT4 transcriptional feedback network for pluripotency of embryonic stem cells
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
POU5F1 (OCT4), SOX2, NANOG Bind the SALL1 Promoter
output
[Complex:R-HSA-2889029] POU5F1:SOX2:NANOG:SALL1 gene [nucleoplasm]
precedingEvent
[BlackBoxEvent:R-HSA-452838] Expression of NANOG - Homo sapiens
[BlackBoxEvent:R-HSA-452894] Expression of SOX2 - Homo sapiens
[BlackBoxEvent:R-HSA-2889036] Translation of OCT4 mRNA - Homo sapiens
releaseDate
2015-12-15
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5246708] Wang, Jianlong, 2014-01-22
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-2972975
summation
[Summation:2972888] POU5F1 (OCT4), SOX2, and NANOG bind the promoter of the SALL...
Referrals
(precedingEvent)
[BlackBoxEvent:R-HSA-452958] Expression of SALL1
(hasEvent)
[Pathway:R-HSA-2892247] POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text