Reactome | NOTCH1 HD domain mutant fragments/Ub-DLL/JAG:NOTCH1 HD domain mutant fragments [extracellular region]

Schema > DefinedSet > Entries

compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2731155] Orlic-Milacic, M, 2012-12-05
crossReference	[DatabaseIdentifier:12020841] Mondo:0004963
dbId	2731153
disease	[Disease:1485587] T-cell acute lymphoblastic leukemia [Disease:1500689] cancer
displayName	NOTCH1 HD domain mutant fragments/Ub-DLL/JAG:NOTCH1 HD domain mutant fragments [extracellular region]
hasMember	[CandidateSet:R-HSA-2730739] NOTCH1 HD domain mutant fragments [extracellular region] - Homo sapiens [Complex:R-HSA-2902223] Ub-DLL/JAG:NOTCH1 HD Domain Mutant Fragments [extracellular region] - Homo sapiens
inDisease	true
maxDepth	7
modified	[InstanceEdit:2902224] Orlic-Milacic, M, 2013-01-03
name	NOTCH1 HD domain mutant fragments/Ub-DLL/JAG:NOTCH1 HD domain mutant fragments
producedByEvent	[Reaction:R-HSA-2730752] NOTCH1 HD domain mutants are cleaved to produce NEXT1 irrespective of ligand binding - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-2731153
updateTrackers	[UpdateTracker:9887601] Update Tracker - [DefinedSet:2731153] NOTCH1 HD domain mutant fragments/Ub-DLL/JAG:NOTCH1 HD domain mutant fragments [extracellular region] - v46:[updateContainedMemberOrCandidate]

(updatedInstance)	[UpdateTracker:9887601] Update Tracker - [DefinedSet:2731153] NOTCH1 HD domain mutant fragments/Ub-DLL/JAG:NOTCH1 HD domain mutant fragments [extracellular region] - v46:[updateContainedMemberOrCandidate]
(output)	[Reaction:R-HSA-2730752] NOTCH1 HD domain mutants are cleaved to produce NEXT1 irrespective of ligand binding

Cite Us!