Reactome | Oligomerization of TRAF6

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Oligomerization of TRAF6 Show undefined attributes

authored	[InstanceEdit:2871799] Niarakis, Anna, 2012-12-21
category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:2730907] Garapati, P V, 2012-12-05
dbId	2730903
displayName	Oligomerization of TRAF6
edited	[InstanceEdit:2454233] Garapati, P V, 2012-08-22
eventOf	[Pathway:R-HSA-2871837] FCERI mediated NF-kB activation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2730904] Auto-ubiquitination of TRAF6 - Homo sapiens
input	[Complex:R-HSA-2685682] DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-166366] TRAF6 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:202452] The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Oligomerization of TRAF6
orthologousEvent	[BlackBoxEvent:R-GGA-2730903] Oligomerization of TRAF6 - Gallus gallus [BlackBoxEvent:R-XTR-2730903] Oligomerization of TRAF6 - Xenopus tropicalis [BlackBoxEvent:R-SSC-2730903] Oligomerization of TRAF6 - Sus scrofa [BlackBoxEvent:R-BTA-2730903] Oligomerization of TRAF6 - Bos taurus [BlackBoxEvent:R-CFA-2730903] Oligomerization of TRAF6 - Canis familiaris [BlackBoxEvent:R-RNO-2730903] Oligomerization of TRAF6 - Rattus norvegicus [BlackBoxEvent:R-MMU-2730903] Oligomerization of TRAF6 - Mus musculus
output	[Complex:R-HSA-2685713] DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer [plasma membrane]
precedingEvent	[Reaction:R-HSA-2730864] Recruitment of TRAF6 to CBM complex by binding to MALT1 - Homo sapiens
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3139040] Roncagalli, Romain, 2013-02-13
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-2730903
summation	[Summation:2685578] BCL10-MALT1 oligomers bind to TRAF6 and this in turn promote...
updateTrackers	[UpdateTracker:9782038] Update Tracker - [BlackBoxEvent:2730903] Oligomerization of TRAF6 - v60:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9782038] Update Tracker - [BlackBoxEvent:2730903] Oligomerization of TRAF6 - v60:[modifyText]
(hasEvent)	[Pathway:R-HSA-2871837] FCERI mediated NF-kB activation
(precedingEvent)	[BlackBoxEvent:R-HSA-2730904] Auto-ubiquitination of TRAF6