Oligomerization of TRAF6

Stable Identifier
R-HSA-2730903
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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Oligomerization of TRAF6
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BCL10-MALT1 oligomers bind to TRAF6 and this in turn promotes the oligomerization of TRAF6 and activates its E3 ligase activity (Sun et al. 2004).

Literature References
PubMed ID Title Journal Year
15125833 The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

Deng, L, Chen, ZJ, Sun, L, Xia, ZP, Ea, CK

Mol Cell 2004
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Authored
Niarakis, A  (2012-12-21)
Reviewed
Roncagalli, R  (2013-02-13)
Created
Garapati, P V  (2012-12-05)
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