Reactome | NOTCH1 I1718T S2 cleavage fragment [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-2730754] NOTCH1 I1718T fragment [extracellular region] - Homo sapiens
created	[InstanceEdit:2730749] Orlic-Milacic, M, 2012-12-04
crossReference	[DatabaseIdentifier:2684880] COSMIC:COSM27418
dbId	2730757
disease	[Disease:1485587] T-cell acute lymphoblastic leukemia [Disease:1500689] cancer
displayName	NOTCH1 I1718T S2 cleavage fragment [extracellular region]
endCoordinate	1720
hasModifiedResidue	[ReplacedResidue:2684884] L-isoleucine 1718 replaced with L-threonine
inDisease	true
name	NOTCH1 I1718T S2 cleavage fragment NOTCH1 Ile1718Thr S2 cleavage fragment NOTCH1 heterodimerization domain mutant I1718T S2 cleavage fragment
referenceEntity	[ReferenceGeneProduct:60520] UniProt:P46531 NOTCH1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2730757
startCoordinate	1665

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