Reactome | NOTCH1 F1592S Extracellular Fragment [extracellular region]

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NOTCH1 F1592S Extracellular Fragment [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-2684856] NOTCH1 F1592S [plasma membrane] - Homo sapiens [Complex:R-HSA-2730750] NOTCH1 F1592S fragment [extracellular region] - Homo sapiens
created	[InstanceEdit:2684854] Orlic-Milacic, M, 2012-11-30
crossReference	[DatabaseIdentifier:12020841] Mondo:0004963 [DatabaseIdentifier:2684848] COSMIC:COSV53024854 [DatabaseIdentifier:2684850] COSMIC:COSM27421
dbId	2684847
disease	[Disease:1485587] T-cell acute lymphoblastic leukemia [Disease:1500689] cancer
displayName	NOTCH1 F1592S Extracellular Fragment [extracellular region]
endCoordinate	1664
hasModifiedResidue	[ReplacedResidue:2684845] L-phenylalanine 1592 replaced with L-serine [ModifiedResidue:1467314] O-fucosyl-L-threonine at 73 [ModifiedResidue:1467403] O-fucosyl-L-threonine at 116 [ModifiedResidue:1467315] O-fucosyl-L-threonine at 194 [ModifiedResidue:1467426] O-fucosyl-L-threonine at 232 [ModifiedResidue:1467344] O-fucosyl-L-threonine at 311 [ModifiedResidue:1467388] O-fucosyl-L-threonine at 349 [ModifiedResidue:1467357] O-fucosyl-L-threonine at 466 [ModifiedResidue:1467431] O-fucosyl-L-threonine at 617 [ModifiedResidue:1467350] O-fucosyl-L-threonine at 692 [ModifiedResidue:1467322] O-fucosyl-L-threonine at 767 [ModifiedResidue:1467374] O-fucosyl-L-threonine at 805 [ModifiedResidue:1467420] O-fucosyl-L-serine at 883 [ModifiedResidue:1467410] O-fucosyl-L-serine at 921 [ModifiedResidue:1467331] O-fucosyl-L-threonine at 997 [ModifiedResidue:1467412] O-fucosyl-L-threonine at 1035 [ModifiedResidue:1467348] O-fucosyl-L-threonine at 1159 [ModifiedResidue:1467303] O-fucosyl-L-threonine at 1197 [ModifiedResidue:1467329] O-fucosyl-L-threonine at 1243 [ModifiedResidue:1467343] O-fucosyl-L-threonine at 1321 [ModifiedResidue:1467324] O-fucosyl-L-threonine at 1362 [ModifiedResidue:1467309] O-fucosyl-L-threonine at 1402 [ModifiedResidue:1467429] O-glucosyl-L-serine at 65 [ModifiedResidue:1467406] O-glucosyl-L-serine at 146 [ModifiedResidue:1467404] O-glucosyl-L-serine at 378 [ModifiedResidue:1467337] O-glucosyl-L-serine at 458 [ModifiedResidue:1467302] O-glucosyl-L-serine at 496 [ModifiedResidue:1467296] O-glucosyl-L-serine at 534 [ModifiedResidue:1467424] O-glucosyl-L-serine at 609 [ModifiedResidue:1467353] O-glucosyl-L-serine at 647 [ModifiedResidue:1467376] O-glucosyl-L-serine at 722 [ModifiedResidue:1467395] O-glucosyl-L-serine at 759 [ModifiedResidue:1467349] O-glucosyl-L-serine at 797 [ModifiedResidue:1467432] O-glucosyl-L-serine at 951 [ModifiedResidue:1467365] O-glucosyl-L-serine at 1027 [ModifiedResidue:1467341] O-glucosyl-L-serine at 1065 [ModifiedResidue:1467362] O-glucosyl-L-serine at 1189 [ModifiedResidue:1467386] O-glucosyl-L-serine at 1273
inDisease	true
maxDepth	1
name	NOTCH1 F1592S Extracellular Fragment NOTCH1 Phe1592Ser Extracellular Fragment NOTCH1 heterodimerization domain mutant F1592S extracellular fragment
referenceEntity	[ReferenceGeneProduct:uniprot:P46531] UniProt:P46531 NOTCH1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2684847
startCoordinate	19

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