Reactome | TLR6/2 ligand:CD14:CD36 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-181410] TLR6:TLR2:ligand:CD14:CD36 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-168950] TLR6:TLR2 is recruited to ligand:CD14:CD36 - Homo sapiens
created	[InstanceEdit:2559467] Shamovsky, V, 2012-11-02
dbId	2559461
displayName	TLR6/2 ligand:CD14:CD36 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-51645] 4xPalmC-CD36 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-166033] GPIN-CD14(20-345) [plasma membrane] [DefinedSet:R-CTR-9628992] TLR6:TLR2 recognized ligand [extracellular region]
inDisease	false
includedLocation	[Compartment:984] extracellular region
isChimeric	false
literatureReference	[LiteratureReference:2428886] Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting
maxDepth	3
modified	[InstanceEdit:9628995] Shamovsky, Veronica, 2018-11-15
name	TLR6/2 ligand:CD14:CD36
producedByEvent	[Reaction:R-HSA-2559464] TLR6/2 ligand associates with CD14 and CD36 within lipid rafts - Homo sapiens
relatedSpecies	[Species:181384] Chlamydia trachomatis
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2559461
updateTrackers	[UpdateTracker:9899966] Update Tracker - [Complex:2559461] TLR6/2 ligand:CD14:CD36 [plasma membrane] - v67:[add_removeHasComponent]

(updatedInstance)	[UpdateTracker:9899966] Update Tracker - [Complex:2559461] TLR6/2 ligand:CD14:CD36 [plasma membrane] - v67:[add_removeHasComponent]
(output)	[Reaction:R-HSA-2559464] TLR6/2 ligand associates with CD14 and CD36 within lipid rafts
(input)	[Reaction:R-HSA-168950] TLR6:TLR2 is recruited to ligand:CD14:CD36
(hasComponent)	[Complex:R-HSA-181410] TLR6:TLR2:ligand:CD14:CD36 [plasma membrane]

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