Reactome | MASTL phosphorylates ENSA

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MASTL phosphorylates ENSA Show undefined attributes

authored	[InstanceEdit:2465904] Orlic-Milacic, M, 2012-09-04
catalystActivity	[CatalystActivity:2430544] protein serine/threonine kinase activity of p-T194,T207,T741-MASTL [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2430553] Orlic-Milacic, M, 2012-08-09
dbId	2430535
displayName	MASTL phosphorylates ENSA
edited	[InstanceEdit:2506916] Gillespie, ME, 2012-09-14
eventOf	[Pathway:R-HSA-2465910] MASTL Facilitates Mitotic Progression - Homo sapiens
followingEvent	[Reaction:R-HSA-2430552] p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-2160964] ENSA [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2430555] Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis [LiteratureReference:2168075] The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	MASTL phosphorylates ENSA
orthologousEvent	[Reaction:R-BTA-2430535] MASTL phosphorylates ENSA - Bos taurus [Reaction:R-SCE-2430535] MASTL phosphorylates ENSA - Saccharomyces cerevisiae [Reaction:R-SPO-2430535] MASTL phosphorylates ENSA - Schizosaccharomyces pombe [Reaction:R-DME-2430535] MASTL phosphorylates ENSA - Drosophila melanogaster [Reaction:R-GGA-2430535] MASTL phosphorylates ENSA - Gallus gallus [Reaction:R-DRE-2430535] MASTL phosphorylates ENSA - Danio rerio [Reaction:R-CFA-2430535] MASTL phosphorylates ENSA - Canis familiaris
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-2430532] p-S67-ENSA [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2430533] CDK1 phosphorylates MASTL - Homo sapiens
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2506915] Mochida, Satoru, 2012-09-26 [InstanceEdit:2506914] Burgess, A, 2012-09-28
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2430535
summation	[Summation:2430560] MASTL (GWL) activates ENSA by phosphorylating it on serine r...

Referrals

(precedingEvent)	[Reaction:R-HSA-2430552] p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D
(hasEvent)	[Pathway:R-HSA-2465910] MASTL Facilitates Mitotic Progression