MASTL phosphorylates ENSA

Stable Identifier
R-HSA-2430535
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MASTL phosphorylates ENSA
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MASTL (GWL) activates ENSA by phosphorylating it on serine residue S67 (Mochida et al. 2010, Gharbi-Ayachi et al. 2010).

Literature References
PubMed ID Title Journal Year
21164013 Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis

Skehel, M, Mochida, S, Hunt, T, Maslen, SL

Science 2010
21164014 The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A

Lorca, T, Burgess, A, Van-Dorsselaer, A, Vigneron, S, Strub, JM, Gharbi-Ayachi, A, Castro, A, Brioudes, E, Labbe, JC

Science 2010
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Catalyst Activity

protein serine/threonine kinase activity of p-T194,T207,T741-MASTL [nucleoplasm]

Physical Entity
p-T194,T207,T741-MASTL [nucleoplasm] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
MASTL phosphorylates ENSA (Bos taurus)
MASTL phosphorylates ENSA (Canis familiaris)
MASTL phosphorylates ENSA (Danio rerio)
MASTL phosphorylates ENSA (Drosophila melanogaster)
MASTL phosphorylates ENSA (Gallus gallus)
MASTL phosphorylates ENSA (Saccharomyces cerevisiae)
MASTL phosphorylates ENSA (Schizosaccharomyces pombe)
MASTL phosphorylates ENSA (Sus scrofa)
MASTL phosphorylates ENSA (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2012-09-04)
Reviewed
Mochida, S  (2012-09-26)
Burgess, A  (2012-09-28)
Created
Orlic-Milacic, M  (2012-08-10)
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