Reactome | IRS-related events triggered by IGF1R

Schema > Pathway > Entries

IRS-related events triggered by IGF1R Show undefined attributes

authored	[InstanceEdit:2428925] May, B, 2012-08-06
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:2428929] May, B, 2012-08-08
crossReference	[DatabaseIdentifier:12819679] BioModels Database:BIOMD0000000449 [DatabaseIdentifier:12819651] BioModels Database:BIOMD0000000356
dbId	2428928
displayName	IRS-related events triggered by IGF1R
edited	[InstanceEdit:2428925] May, B, 2012-08-06
eventOf	[Pathway:R-HSA-2428924] IGF1R signaling cascade - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-2428930] IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 - Homo sapiens [Reaction:R-HSA-2428922] IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 - Homo sapiens [Reaction:R-HSA-2428926] IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 - Homo sapiens [Pathway:R-HSA-112399] IRS-mediated signalling - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-12-13
literatureReference	[LiteratureReference:2454001] Biological & physiological aspects of action of insulin-like growth factor peptide family [LiteratureReference:2454014] Insulin/IGF-I and related signaling pathways regulate aging in nondividing cells: from yeast to the mammalian brain [LiteratureReference:2454041] Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances [LiteratureReference:2454045] Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer [LiteratureReference:2454007] The IGF system [LiteratureReference:2454004] The type 1 insulin-like growth factor receptor pathway
maxDepth	6
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	IRS-related events triggered by IGF1R
orthologousEvent	[Pathway:R-PFA-2428928] IRS-related events triggered by IGF1R - Plasmodium falciparum [Pathway:R-SCE-2428928] IRS-related events triggered by IGF1R - Saccharomyces cerevisiae [Pathway:R-SPO-2428928] IRS-related events triggered by IGF1R - Schizosaccharomyces pombe [Pathway:R-DDI-2428928] IRS-related events triggered by IGF1R - Dictyostelium discoideum [Pathway:R-CEL-2428928] IRS-related events triggered by IGF1R - Caenorhabditis elegans [Pathway:R-DME-2428928] IRS-related events triggered by IGF1R - Drosophila melanogaster [Pathway:R-GGA-2428928] IRS-related events triggered by IGF1R - Gallus gallus [Pathway:R-XTR-2428928] IRS-related events triggered by IGF1R - Xenopus tropicalis [Pathway:R-DRE-2428928] IRS-related events triggered by IGF1R - Danio rerio [Pathway:R-SSC-2428928] IRS-related events triggered by IGF1R - Sus scrofa [Pathway:R-BTA-2428928] IRS-related events triggered by IGF1R - Bos taurus [Pathway:R-CFA-2428928] IRS-related events triggered by IGF1R - Canis familiaris [Pathway:R-RNO-2428928] IRS-related events triggered by IGF1R - Rattus norvegicus [Pathway:R-MMU-2428928] IRS-related events triggered by IGF1R - Mus musculus
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2566980] Holzenberger, Martin, 2012-11-09
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-2428928
summation	[Summation:2454015] The phosphorylated type 1 insulin-like growth factor recepto...
updateTrackers	[UpdateTracker:9780253] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v63:[updateContainedPathway] [UpdateTracker:9778735] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v67:[addHasEvent, modifyText] [UpdateTracker:9779659] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v65:[removeHasEvent, updateContainedPathway] [UpdateTracker:9780791] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v62:[updateContainedPathway] [UpdateTracker:9784822] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v53:[updateContainedPathway]

Referrals

(updatedInstance)

[UpdateTracker:9780253] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v63:[updateContainedPathway]
[UpdateTracker:9778735] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v67:[addHasEvent, modifyText]
[UpdateTracker:9779659] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v65:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9780791] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v62:[updateContainedPathway]
[UpdateTracker:9784822] Update Tracker - [Pathway:2428928] IRS-related events triggered by IGF1R - v53:[updateContainedPathway]

(hasEvent)

[Pathway:R-HSA-2428924] IGF1R signaling cascade

Cite Us!