Reactome | SREBP1A,2 binds the SC5DL promoter

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SREBP1A,2 binds the SC5DL promoter Show undefined attributes

authored	[InstanceEdit:2426159] May, B, 2012-07-26
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2426145] May, B, 2012-07-27
dbId	2426164
displayName	SREBP1A,2 binds the SC5DL promoter
edited	[InstanceEdit:2426159] May, B, 2012-07-26
eventOf	[Pathway:R-HSA-2426168] Activation of gene expression by SREBF (SREBP) - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-1655852] Expression of Lathosterol Oxidase (SC5D, SC5DL) - Homo sapiens
input	[Complex:R-HSA-381204] NF-Y [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-2394001] SC5DL gene [nucleoplasm] [Complex:R-HSA-2065551] SREBP1A,2 dimer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1655587] Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes [LiteratureReference:1655606] Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SREBP1A,2 binds the SC5DL promoter SREBF1A/2 Binds the SC5DL Promoter
output	[Complex:R-HSA-2426140] SREBP1A,2:NF-Y:SC5DL gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2065539] SREBP1A,1C,2:Importin beta-1 dissociates - Homo sapiens
releaseDate	2012-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2457630] Liang, Guosheng, 2012-08-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2426164
summation	[Summation:2426222] SREBP1A (SREBF1A) or SREBP2, together with NF-Y, bind and tr...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-1655852] Expression of Lathosterol Oxidase (SC5D, SC5DL)
(hasEvent)	[Pathway:R-HSA-2426168] Activation of gene expression by SREBF (SREBP)

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