Reactome | COMP binds collagen, fibronectin, aggrecan and matrilins

Schema > Reaction > Entries

COMP binds collagen, fibronectin, aggrecan and matrilins Show undefined attributes

authored	[InstanceEdit:2976617] Jupe, S, 2013-01-10
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2424251] Jupe, S, 2012-07-20
dbId	2424252
displayName	COMP binds collagen, fibronectin, aggrecan and matrilins
edited	[InstanceEdit:3318356] Jupe, S, 2013-04-26
eventOf	[Pathway:R-HSA-3000178] ECM proteoglycans - Homo sapiens
input	[DefinedSet:R-HSA-2426282] COMP interactors [extracellular region] [Complex:R-HSA-2426264] COMP pentamer [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2299622] Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen [LiteratureReference:2426246] Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX [LiteratureReference:2426330] Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin [LiteratureReference:2426306] Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias [LiteratureReference:2299634] Interaction of cartilage matrix protein with aggrecan. Increased covalent cross-linking with tissue maturation [LiteratureReference:2426295] Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	COMP binds collagen, fibronectin, aggrecan and matrilins
output	[Complex:R-HSA-2426278] COMP pentamer:COMP interactors [extracellular region]
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3597636] Narayanan, Venkatesan, 2013-05-21 [InstanceEdit:3597676] Ricard-Blum, Sylvie, 2013-05-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2424252
summation	[Summation:2424247] Cartilage oligomeric matrix protein (COMP, thrombospondin-5)...

Referrals

(hasEvent)

[Pathway:R-HSA-3000178] ECM proteoglycans

Cite Us!