Reactome | SeMet is converted to AdoSeMet by MAT

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SeMet is converted to AdoSeMet by MAT Show undefined attributes

authored	[InstanceEdit:5422928] Williams, MG, 2014-05-06
catalystActivity	[CatalystActivity:5359023] selenomethionine adenosyltransferase activity of MAT1A multimers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2408534] Williams, MG, 2012-07-17
crossReference	[DatabaseIdentifier:12667930] RHEA:31212 [DatabaseIdentifier:9930577] RHEA:31212
dbId	2408551
displayName	SeMet is converted to AdoSeMet by MAT
edited	[InstanceEdit:6793109] D'Eustachio, Peter, 2015-08-29
eventOf	[Pathway:R-HSA-2408508] Metabolism of ingested SeMet, Sec, MeSec into H2Se - Homo sapiens
followingEvent	[Reaction:R-HSA-2408544] AdoSeMet is converted to AdeSeHCys by MetTrans(1) - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-5357707] SeMet [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5359191] Effects of selenomethionine on cell growth and on S-adenosylmethionine metabolism in cultured malignant cells
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SeMet is converted to AdoSeMet by MAT ATP + H2O + L-selenomethionine => diphosphate + L-adenosylselenomethionine + phosphate
orthologousEvent	[Reaction:R-PFA-2408551] SeMet is converted to AdoSeMet by MAT - Plasmodium falciparum [Reaction:R-SCE-2408551] SeMet is converted to AdoSeMet by MAT - Saccharomyces cerevisiae [Reaction:R-SPO-2408551] SeMet is converted to AdoSeMet by MAT - Schizosaccharomyces pombe [Reaction:R-DDI-2408551] SeMet is converted to AdoSeMet by MAT - Dictyostelium discoideum [Reaction:R-CEL-2408551] SeMet is converted to AdoSeMet by MAT - Caenorhabditis elegans [Reaction:R-DME-2408551] SeMet is converted to AdoSeMet by MAT - Drosophila melanogaster [Reaction:R-GGA-2408551] SeMet is converted to AdoSeMet by MAT - Gallus gallus [Reaction:R-XTR-2408551] SeMet is converted to AdoSeMet by MAT - Xenopus tropicalis [Reaction:R-DRE-2408551] SeMet is converted to AdoSeMet by MAT - Danio rerio [Reaction:R-SSC-2408551] SeMet is converted to AdoSeMet by MAT - Sus scrofa [Reaction:R-BTA-2408551] SeMet is converted to AdoSeMet by MAT - Bos taurus [Reaction:R-CFA-2408551] SeMet is converted to AdoSeMet by MAT - Canis familiaris [Reaction:R-RNO-2408551] SeMet is converted to AdoSeMet by MAT - Rattus norvegicus [Reaction:R-MMU-2408551] SeMet is converted to AdoSeMet by MAT - Mus musculus
output	[SimpleEntity:R-ALL-5357652] AdoSeMet [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6793106] Rush, MG, 2015-08-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2408551
summation	[Summation:5422888] Methionine adenosyltransferases (MAT multimers) consisting o...

Referrals

(hasEvent)	[Pathway:R-HSA-2408508] Metabolism of ingested SeMet, Sec, MeSec into H2Se
(precedingEvent)	[Reaction:R-HSA-2408544] AdoSeMet is converted to AdeSeHCys by MetTrans(1)