Methionine adenosyltransferases (MAT multimers) consisting of a S-adenosylmethionine synthase isoform type-1 (MAT1A) homodimer and a MAT1A: S-adenosylmethionine synthase isoform type-2 (MAT2A) heterodimer are responsible for the conversion of selenomethionine (SeMet) and ATP into Se-adenosylselenomethionine (AdoSeMet), orthophosphate (Pi), and diphosphate (PPi) (Kajander et al. 1990).
Akerman, KK, Pajula, RL, Kärenlampi, SO, Martikainen, H, Harvima, RJ, Kauppinen, L, Kajander, EO
selenomethionine adenosyltransferase activity of MAT1A multimers [cytosol]
© 2023 Reactome