Reactome | HSPG2 (perlecan) binds alpha-dystroglycan

Schema > Reaction > Entries

authored	[InstanceEdit:2426629] Jupe, S, 2012-08-08
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:2396250] Jupe, S, 2012-07-09
dbId	2396395
displayName	HSPG2 (perlecan) binds alpha-dystroglycan
edited	[InstanceEdit:4090280] Jupe, S, 2013-08-13
eventOf	[Pathway:R-HSA-3000178] ECM proteoglycans - Homo sapiens
input	[Complex:R-HSA-2328140] Dystroglycan [plasma membrane] [EntityWithAccessionedSequence:R-HSA-1011570] HSPG2(22-4391) [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2328102] Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	HSPG2 (perlecan) binds alpha-dystroglycan
orthologousEvent	[Reaction:R-CEL-2396395] HSPG2 (perlecan) binds alpha-dystroglycan - Caenorhabditis elegans [Reaction:R-DME-2396395] HSPG2 (perlecan) binds alpha-dystroglycan - Drosophila melanogaster
output	[Complex:R-HSA-2426324] HSPG2:Dystroglycan [plasma membrane]
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4088447] Ricard-Blum, Sylvie, 2013-08-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2396395
summation	[Summation:2396298] HSPG2 (perlecan) is a modular proteoglycan primarily located...

(hasEvent)

Cite Us!