Reactome | Phosphorylation of DAP12

Schema > Reaction > Entries

Phosphorylation of DAP12 Show undefined attributes

authored	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
catalystActivity	[CatalystActivity:2395432] protein tyrosine kinase activity of FYN,LCK [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2395415] Garapati, P V, 2012-06-29
dbId	2395439
displayName	Phosphorylation of DAP12
edited	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
eventOf	[Pathway:R-HSA-2424491] DAP12 signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-210289] Recruitment of SYK to p-DAP12 - Homo sapiens
inferredFrom	[Reaction:R-MMU-2395436] Phosphorylation of DAP12 - Mus musculus
input	4 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-2395430] DAP12 receptors:DAP12 dimer [plasma membrane] [DefinedSet:R-HSA-2395419] FYN,LCK [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylation of DAP12
output	4 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-2395423] DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane]
precedingEvent	[Reaction:R-HSA-2172126] DAP12 interacts with NKG2C - Homo sapiens [Reaction:R-HSA-210295] Interaction of DAP12 and NKG2D - Homo sapiens [Reaction:R-HSA-210300] Interaction of DAP12 and TREM2 - Homo sapiens
releaseDate	2012-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2428957] Lanier, Lewis L, 2012-08-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2395439
summation	[Summation:2395427] Crosslinking of receptors associated with DAP12 leads to pho...

Referrals

(hasEvent)	[Pathway:R-HSA-2424491] DAP12 signaling
(precedingEvent)	[Reaction:R-HSA-210289] Recruitment of SYK to p-DAP12
(inferredTo)	[Reaction:R-MMU-2395436] Phosphorylation of DAP12

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