Reactome | DAP12 interacts with NKG2C

Schema > Reaction > Entries

DAP12 interacts with NKG2C Show undefined attributes

authored	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2172125] Garapati, P V, 2012-03-28
dbId	2172126
displayName	DAP12 interacts with NKG2C
edited	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
eventOf	[Pathway:R-HSA-2172127] DAP12 interactions - Homo sapiens
followingEvent	[Reaction:R-HSA-2395439] Phosphorylation of DAP12 - Homo sapiens
input	[Complex:R-HSA-2326867] CD94:NKG2C:HLA-E [plasma membrane] [Complex:R-HSA-548940] DAP12 dimer [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2326773] Association of DAP12 with activating CD94/NKG2C NK cell receptors [LiteratureReference:2326775] The CD94/NKG2C killer lectin-like receptor constitutes an alternative activation pathway for a subset of CD8+ T cells
maxDepth	1
modified	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
name	DAP12 interacts with NKG2C
orthologousEvent	[Reaction:R-CFA-2172126] DAP12 interacts with NKG2C - Canis familiaris [Reaction:R-RNO-2172126] DAP12 interacts with NKG2C - Rattus norvegicus [Reaction:R-MMU-2172126] DAP12 interacts with NKG2C - Mus musculus
output	[Complex:R-HSA-2326822] HLA-E:CD94:NKG2C:DAP12 [plasma membrane]
precedingEvent	[Reaction:R-HSA-2130151] Dimerization of DAP12 - Homo sapiens
releaseDate	2012-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2428957] Lanier, Lewis L, 2012-08-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2172126
summation	[Summation:2326842] NKG2C, a C-type lectin-like surface receptor, is a member of...

Referrals

(hasEvent)	[Pathway:R-HSA-2172127] DAP12 interactions
(precedingEvent)	[Reaction:R-HSA-2395439] Phosphorylation of DAP12

Cite Us!