Reactome | STAB2:ligand is endocytosed

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STAB2:ligand is endocytosed Show undefined attributes

authored	[InstanceEdit:3000476] May, B, 2013-01-26 [InstanceEdit:3222522] Neyen, Claudine, 2013-03-22
category	omitted
compartment	[Compartment:24337] endocytic vesicle membrane [Compartment:876] plasma membrane
created	[InstanceEdit:2247509] May, B, 2012-05-12
dbId	2247511
displayName	STAB2:ligand is endocytosed
edited	[InstanceEdit:2230995] May, B, 2012-05-06
eventOf	[Pathway:R-HSA-3000497] Scavenging by Class H Receptors - Homo sapiens
input	[Complex:R-HSA-2203471] STAB2:Ligand [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2213050] Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins [LiteratureReference:2197732] FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products [LiteratureReference:2197756] Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	STAB2:ligand is endocytosed
orthologousEvent	[BlackBoxEvent:R-GGA-2247511] STAB2:ligand is endocytosed - Gallus gallus [BlackBoxEvent:R-SSC-2247511] STAB2:ligand is endocytosed - Sus scrofa [BlackBoxEvent:R-BTA-2247511] STAB2:ligand is endocytosed - Bos taurus [BlackBoxEvent:R-CFA-2247511] STAB2:ligand is endocytosed - Canis familiaris [BlackBoxEvent:R-MMU-2247511] STAB2:ligand is endocytosed - Mus musculus
output	[Complex:R-HSA-2247504] STAB2:Ligand [endocytic vesicle membrane]
precedingEvent	[Reaction:R-HSA-2203479] STAB2 (FEEL-2) binds ligands - Homo sapiens
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3222522] Neyen, Claudine, 2013-03-22
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-2247511
summation	[Summation:2512809] The STAB2:ligand complex is endocytosed (Tamura et al. 2003,...

Referrals

(hasEvent)

[Pathway:R-HSA-3000497] Scavenging by Class H Receptors