Reactome | STAB2:Ligand [plasma membrane]

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STAB2:Ligand [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-HSA-2247511] STAB2:ligand is endocytosed - Homo sapiens
created	[InstanceEdit:2203478] May, B, 2012-04-22
dbId	2203471
displayName	STAB2:Ligand [plasma membrane]
hasComponent	[DefinedSet:R-HSA-2197765] Ligands of STAB2 [extracellular region] [EntityWithAccessionedSequence:R-HSA-2160853] STAB2(1136-2551) [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-2203471] STAB2:Ligand [plasma membrane] - Mus musculus [Complex:R-CFA-2203471] STAB2:Ligand [plasma membrane] - Canis familiaris [Complex:R-BTA-2203471] STAB2:Ligand [plasma membrane] - Bos taurus [Complex:R-SSC-2203471] STAB2:Ligand [plasma membrane] - Sus scrofa [Complex:R-GGA-2203471] STAB2:Ligand [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:2160899] Endocytic function, glycosaminoglycan specificity, and antibody sensitivity of the recombinant human 190-kDa hyaluronan receptor for endocytosis (HARE) [LiteratureReference:2160865] Expression, processing, and glycosaminoglycan binding activity of the recombinant human 315-kDa hyaluronic acid receptor for endocytosis (HARE) [LiteratureReference:2197732] FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products [LiteratureReference:2197749] FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities [LiteratureReference:2197746] Purification and molecular identification of the human hyaluronan receptor for endocytosis [LiteratureReference:2197719] Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor [LiteratureReference:2197761] Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins [LiteratureReference:2160872] The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin [LiteratureReference:2197741] The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E
maxDepth	5
modified	[InstanceEdit:2512716] May, B, 2012-10-07
name	STAB2:Ligand FEEL2:Ligand
producedByEvent	[Reaction:R-HSA-2203479] STAB2 (FEEL-2) binds ligands - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2203471

Referrals

(output)	[Reaction:R-HSA-2203479] STAB2 (FEEL-2) binds ligands
(input)	[BlackBoxEvent:R-HSA-2247511] STAB2:ligand is endocytosed

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